หมายเลขหนังสือ | 1 |
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ชื่องานวิจัย | Hematologic Indices as Predictors of Mortality of HIV/AIDS Patients, Thailand |
ชื่อผู้แต่ง | S. Tansuphasawadikul1, Ittiravivongs A., Kitayaporn D., Kaewkungwal J., Tanchanpong C., Limpakarnjanarat K. and Mastro TD. |
สถาบัน | 1 Bamrasnaradura Hospital, Ministry of Public Health |
ที่มา | Tansuphasawadikul S., Ittiravivongs A., Kitayaporn D., Kaewkungwal J., Tanchanpong C., Limpakarnjanarat K. and Mastro TD. |
คำสำคัญ | AIDS, prognosis, hematological |
ปี พ.ศ. | 2538 |
จำนวนหน้า | 0 |
ประเภทเอกสาร | บทคัดย่อ |
บทคัดย่อ | Objectives : To evaluate routine hematologic indices as predictors of mortality among HIV+ patients on their first admission to a tertiary care infectious disease hospital in Thailand. Methods : Complete blood count (CBC) data on admission from 715 HIV+ patients (>=14 yrs.) admitted for the first time were analyzed. CBC values except differential white count were obtained from an automated COULTER JT3. Results : of 715 patients, 627 (87.8%) had AIDS, 152 (21.3%) died during the admission. Anemia was common, 89.2% had hemoglobin <13.0 g/dl and 91.9% had hematocrit <40.0% ; whereas 23%, 19% and 76% were thrombocytopenic (<150,000 cells/ microlitre), leukopenic (<3,800 cells/ microlitre), and lymphocytopenic (<1,500 cells/ microlitre), respectively. Patients who died during this admission had lower mean hemoglobin, platelet count, MCV, and total lymphocytes (p<0.05) than those who survied. However, on logistic regression analysis controlling for age, sex and AIDS ; among CBC data only low platelets (<150,000 cells/ microlitre) was significantly related with mortality, with odds ratios of 2.78 (95% CI = 1.9, 4.2). Discussion and Conclusions : Among hematologic indices, when controlling for AIDS diagnosis, low platelet counts was associated with mortality among HIV+ persons admitted to this hospital. |