| บทคัดย่อ | Objectives : To evaluate routine hematologic indices as predictors of mortality among HIV+ patients on their first admission to a tertiary care infectious disease hospital in Thailand.
Methods : Complete blood count (CBC) data on admission from 715 HIV+ patients (>=14 yrs.) admitted for the first time were analyzed. CBC values except differential white count were obtained from an automated COULTER JT3.
Results : of 715 patients, 627 (87.8%) had AIDS, 152 (21.3%) died during the admission. Anemia was common, 89.2% had hemoglobin <13.0 g/dl and 91.9% had hematocrit <40.0% ; whereas 23%, 19% and 76% were thrombocytopenic (<150,000 cells/ microlitre), leukopenic (<3,800 cells/ microlitre), and lymphocytopenic (<1,500 cells/ microlitre), respectively. Patients who died during this admission had lower mean hemoglobin, platelet count, MCV, and total lymphocytes (p<0.05) than those who survied. However, on logistic regression analysis controlling for age, sex and AIDS ; among CBC data only low platelets (<150,000 cells/ microlitre) was significantly related with mortality, with odds ratios of 2.78 (95% CI = 1.9, 4.2).
Discussion and Conclusions : Among hematologic indices, when controlling for AIDS diagnosis, low platelet counts was associated with mortality among HIV+ persons admitted to this hospital. |
